South Africa toured the West Indies in Aug/Sep 2021 for a series of three T20 Internationals and five One-Day Internationals in Antigua.
- First T20I (no result)
- Second T20I (South Africa by 50 runs)
- Third T20I (West Indies by 9 wickets)
- First ODI (South Africa by 8 wickets)
- Second ODI (South Africa by 9 wickets)
- Third ODI (South Africa by 8 wickets)
- Fourth ODI (South Africa by 35 runs)
- Fifth ODI (Tied. West Indies won super over)